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Y Axis Organism
Hosts
Dissimilarity
NA
Organism
Species
Dissimilarity
NA
Physico-
chemical
Dissimilarity
NA
Functional
Dissimilarity *
NA
Functional
Dissimilarity *
Physico-
chemical
Dissimilarity
Organism
Species
Dissimilarity
Organism
Hosts
Dissimilarity
X Axis





First, we classified the entire sequences of Swiss-Prot into 20^4 (= 160,000) patterns according to its C-terminal four amino acids. Then, we defined the frequency of Gene Ontology terms annotated to sequences with the same pattern as the function of each pattern. Finally, we calculated the dissimilarity between the functions of each pattern with Tanimoto coefficient extended so as to handle real number.
First, we assign the values of hydrophobicity, hydrophilicity, amphiphilicity, mean polarity, positive charge, and negative charge provided in AAindex database to each amino acid of each C-terminal four amino acids pattern. Then, we defined the values of each pattern as the physicochemical property of each pattern. Finally, we calculated the dissimilarity between the physicochemical properties of each pattern with Tanimoto coefficient extended so as to handle real number.
First, we classified the entire sequences of Swiss-Prot into 20^4 (= 160,000) patterns according to its C-terminal four amino acids. Then, we defined the frequency of organism species which is the source of each sequence with the same pattern as the organism species characteristic of each pattern. Finally, we calculated the dissimilarity between the characteristics of each pattern with Tanimoto coefficient extended so as to handle real number.
First, we classified the entire sequences of Swiss-Prot into 20^4 (= 160,000) patterns according to its C-terminal four amino acids. Then, we defined the frequency of organism hosts which may be infected by the virus which is the source of each sequence with the same pattern as the organism hosts characteristic of each pattern. Finally, we calculated the dissimilarity between the characteristics of each pattern with Tanimoto coefficient extended so as to handle real number.